Because there were very little advances in modern medicine, most of the remedies were quite ineffective. From simple charms and herbs to very severe remedies that actually did a lot of harm instead of good. One of those severe remedies was where they forced the patient to bleed an extreme amount. This was in hopes that the sickness would "bleed out" along with the blood. You can obviously tell that this didn't work whatsoever.
There were other side effects, but they were more social than medical. Some people would just go through the streets and do what they please. Such as stuffing themselves with food, because they would tell themselves "what does it matter? I'm going to die in 2 days anyway". Others became very closed off until their death, not leaving the house and barely having any social interaction. But no matter what, you would become a social outcast. Nobody would go near you or talk to you what so ever.